Research Areas Biosensor platform for medical diagnosis and/or environmental toxin detection

Research Interests BIOSENSOR PLATFORM TECHNOLOGY FOR POINT-OF-CARE TESTING
The biosensor platform based on microfluidics technology is a compact device with all necessary instrumentation in a portable and easy-to-use format. These devices enable point-of-care testing (POCT) to be performed at patient care sites or environmental sampling sites. POCT devices provide rapid test results with the potential to improve patient care in the medical field. Research activities in the laboratory are focused on development of a platform technology for rapid antigen diagnosis/rapid molecular diagnosis device capable of on-site examination.

FUNCTIONAL NANO-BIO MATERIALS
In the past few years, biomaterial-based nanoparticles with multifunctional properties have received a lot of attention. The fine-tuning ease of nano-biomaterials makes them top candidates for biotechnology applications. Research activities in the laboratory are focused on the design and manufacture of novel nanostructured materials for a wide range of applications including environmental biosensing and medical biosensing. In particular, it focuses on its application to the development of biosensor with high sensitivity.

Selected Publications Myeong-Jun Lee, Eun-Sol Lee, Tae-Hwan Kim, Ju-Won Jeon, YongTae Kim, Byung-Keun Oh, “Detection of thioredoxin-1 using ultra-sensitive ELISA with enzyme-encapsulated human serum albumin nanoparticle”, Nano Convergence 6 (2019) 1-7.

Jinho Yoon, Taek Lee, Jinhee Jo, Byung-Keun Oh, Jeong-Woo Choi, “Electrochemical H2O2 biosensor composed of myoglobin on MoS2 nanoparticle-graphene oxide hybrid structure”, Biosensors and Bioelectronics 93 (2017) 14-20.

Jin-Ha Choi, Hai-Jin Hwang, Seung Won Shin, Jeong-Woo Choi, Soong Ho Um, Byung-Keun Oh, “A novel albumin nanocomplex containing both small interfering RNA and gold nanorods for synergetic anticancer therapy” Nanoscale 7 (2015) 9229-9237.

Jin-Ha Choi, Han Kim, Jae-Hak Choi, Jeong-Woo Choi, Byung-Keun Oh. “Signal Enhancement of Silicon Nanowire-Based Biosensor for Detection of Matrix Metalloproteinase-2 Using DNA-Au Nanoparticle Complexes” ACS applied materials & interfaces 5 (2013) 12023-12028.

Jin Ha Choi, Hyun Soo Kim, Jeong-Woo Choi, Jong Wook Hong, Young-Kee Kim, Byung-Keun Oh, “A novel Au-nanoparticle biosensor for the rapid and simple detection of PSA using a sequence-specific peptide cleavage reaction” Biosensors and Bioelectronics 49 (2013) 415-419.

Professional Experience Postdoctoral fellow (Northwestern University, 2004-2006)
Visiting Professor (Auburn University, 2012)